Bubble Up Pizza Casserole

1 pound lean ground beef (you can also use ground turkey or sausage for variation)
1 small onion, diced
2 cloves garlic, minced
1 can (15 ounces) pizza sauce
1 package (12 ounces) refrigerated biscuit dough (such as Pillsbury Grands), cut into quarters
2 cups shredded mozzarella cheese
1 cup shredded cheddar cheese (optional for extra cheesiness)
1/2 cup sliced pepperoni (you can also use other pizza toppings like bell peppers, mushrooms, olives, etc., according to your preference)
1 teaspoon Italian seasoning
1/2 teaspoon garlic powder
Salt and pepper to taste
Cooking spray for greasing the baking dish
Instructions for Making Bubble Up Pizza Casserole
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